Symbol Name ID |
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast) MGI:2449307 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
decreased T cell proliferation |
thymus hypoplasia |
abnormal T cell receptor beta chain V(D)J recombination |
decreased double-positive T cell number |
decreased granulocyte number |
abnormal B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
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Availability | Mouse Genotype | |||||||||
Upf2tm1Btp/Upf2tm1Btp Tg(Mx1-cre)1Cgn/0 (conditional) |
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Tg(Lck-cre)548Jxm/? Upf2tm1Btp/Upf2tm1Btp (conditional) |
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Upf2tm1Btp/Upf2tm1Btp Lyz2tm1(cre)Ifo/? (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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